As an advanced practice nurse assisting physicians in the diagnosis and treatment of disorders, it is important to not only understand the impact of disorders on the body, but also the impact of drug treatments on the body. The relationships between drugs and the body can be described by pharmacokinetics and pharmacodynamics.
Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body.
When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.
For this Discussion, you reflect on a case from your past clinical experiences and consider how a patient’s pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.
Review the Resources for this module and consider the principles of pharmacokinetics and pharmacodynamics.
Reflect on your experiences, observations, and/or clinical practices from the last 5 years and think about how pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug.
Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes, such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.
Think about a personalized plan of care based on these influencing factors and patient history in your case study.
Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples.
Content is very important to me, so I want you to make sure that your posts and writings for assignments are substantial and are from credible sources (i.e., textbook, publications, etc.). Sources such as drugs.com, Medscape.com, etc., can be used, but they CANNOT be the only sources you have. The latter are set up as information sites only and will not always be accurate. In your discussions, as well as assignments, you should be focusing on the medication parts of the assignment. This is a pharmacology class, so I want you to be researching how the disease is treated, why those treatments the best for the specific disease state, what complications come from treatment, how to avert possible problems with treatment, how to deal with comorbidities during treatments, etc. This is not all inclusive, but some of the things I want you to be thinking about. This will help ensure that you will get the most out of this class and sharpen your reasoning skills as to why certain treatments are used once you are in practice. ust because a Discussion post is longer, does not mean it is better in my estimation. I want you to be able to find the correct information and efficiently write your thoughts and opinions. References nothing less than 5 years.
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